In a word, yes. I found that Minish Cap was my favourite handheld Zelda game, and my third favourite of all Zeldas, after Twilight Princess and Majora's Mask. It's shrinking/growing is a great way of having puzzles, and the combat is great, too.
I'm a dragon. You can probably see that from my avatar. Hehe.
After playing many different Zelda games, I found the puzzles in Minish Cap to be refreshing. They were different and challenging. I'd definitely say it's the best handheld game I've played, but for best 2D Zelda, I still prefer Four Swords Adventures, but that's just me