Yes I know, I'm stealing ideas from the character thread. xP
Except this narrows it down to villains. As for who I think was best...
Mr. L = Awesomest. Villain. Ever. Who can be more badass and awesome to fight against than this guy and his Brobot? HAVE AT YOU!
OMG, Black Knight from Fire Emblem 9 and 10. Ike's biggest enemy. He murdered Ike's father, can take out whole armies by himself, and has a mysterious background up until you learn who he really is. He's also playable in Fire Emblem 10 for a few chapters in Part 1. Wants to help Daein, but is still badass.
Oh, and I can't forget Vaati. My favorite Zelda villain. He has an awesome theme, awesome personality, and three awesome forms at the end of
TMC. He's also plain badass for sneaking into the castle, taking over the King's body, and turning everyone to stone while trying to kill Zelda by taking the Light Force. Vaati ftw.
As for who I think is the worst...
Pathetic. Just completely pathetic. Extremely easy battle, extremely crazy and psycho way of fighting back, and really really retarded looking appearance in the non-mask forms. Majora was the crappiest villain to ever be in a video game, imo, and I hope not even the mask returns.