I somewhat agree with Hungry Hippo, but I do confess I'd be interested in a Warcraft movie....
However, most games I'd even half-want to see take on the risk of being brought to movie form..I'd prefer it to be a movie based EXACTLY on the game.
Like, a movie that basically takes the cutscenes from a game, adds ones to fill in the gameplay sections and gets graphically updated with CGI Square-Enix style. No 'reimaginings' of games as movies or what Uncharted almost wound up being.
So, I guess what I'm saying is don't involve Hollywood =P
Anything Hollywood got its grubby, greedy hands on would be ruined, because they'd involve cheesy cliched romance, make the villain ridiculously flamboyant, add an obscene amount of cursing, and overdo everything else that made the game awesome.
MGS? They'd overplay Raiden and probably make him gay. Snake would be a cliched action movie hero like Rambo.
Assassin's Creed? They'd WAY overdo the flirting each assassin does, and make them complete cocky jerks. The fight scenes might be good, though.
Metroid? Either Samus would be a weak, whining woman who couldn't get the job done without agonizing over killing every single alien parasite she came across, or be an over-the-top gung-ho feminist.
Halo? It would be completely focused on how much the Spartans are killing machines, and hardly give any attention to the struggle humanity's going through, and how close they came to getting wiped out. Master Chief would be a Mary Sue. Cliche, through and through.
Mario... Yeah I don't see that turning out well at all.
Many games are completely unsuited for the silver screen, but it really depends on the director more than the subject matter. I feel like Ridley Scott could make something pretty awesome out of Halo or Metroid. Pierre Morel could make an awesome Deus Ex, and a Half-Life movie by Sam Raimi would blow my mind. Video game movies aren't inherently bad, it's just that they're usually made by untalented people, starring cheap actors and produced by a studio looking for audiences to cash in on.
It's 1970's America, two detectives; detective Peter Van and detective Orlandi Augymubeng, have 4 hours to match a face of the Crescent Moon Killer. Luckily, an evil mastermind known as "Billy the Pre-Teen" has contacted them via Skype.
Only Billy knows the true face of the killer. But as per usual, Billy don't play fair, the agents have to test their brains and indeed minds to knock down 23 photographs of potential murderers and find the 1 photo that pictures the actual murderer.
Augymubeng did it, he was sick of being the only Ghanian detective and felt throughout his career that he was being limited to how far he could advance due to the prejudice 1970's America had against Black police officers so he committed the ultimate crime, and then he was going to solve it and become the most decorated detective in the world, and he would've got away with it too if it wasn't for that pesky pre-teen!