OMG I wanted this for a long long time. Except for that one line in Twilight Princess, and the ending for Spirit Tracks, you could only give one answer. Choose the other answer and they make you go back and pick the right answer.
In Skyward Sword during a lot of conversations you get two or three answers to choose from. In most cases they say one line different back to you. Other times it can make more of a difference. One guy would not give me a tip(hint) because I chose the wrong anwer. Lastly, the results could come out different. During the one side quest you get a letter. You can give that letter to two different people. The results are different but the prize is the same.
Things like this give the game some replay value, if you want to see all the different outcomes for the different answers.
There's many other things I love about this game as well. It has a good chance to be #1, but I won't decide this until I beat it a few times.