I've never played Resident Evil, but I highly doubt there is such thing as a villain greater than Legato Bluesummers.
Then have an video duel! You show me an vid of Legato that is badass, then I show an video of Wesker that is even MORE badass. And if I can't find one, well, then you win. But if I do top your vids, I win.
No. I never found anything impressive about those Wesker videos. I have seen a million better villains. Hell, Sephiroth did something similar to that whole virus thing, and Advent Children still sucked major ass.