Apparently in the NP interview, his comment could just be on the art style. Then again, this could be a completely different response.

“I don’t think it’s going to change dramatically. We are doing it on the Wii [console]. That being said, we can look at Twilight Princess - it was built to run on both GameCube and Wii, and this one will be running only on Wii, so I think there will be differences inherent to the fact that it’s only on this platform.”

SOURCE
http://www.nintendoeverything.com/?p=19117#comments

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