Ignoring everything outside the edges of the panels, your comic is actually pretty good. Perhaps not incredibly original (I hate to say it, but anime-esque plots with Sonic edits have been done to death in sprite comics), but the presentation is sharp, the writing is easy to follow and the graphics are pleasing and polished.

That being said, outside the panels is a mess, and this seems to be a recurring theme with your work. Your panel placement is seeming random. There is a more-or-less left-to-right up-to-down placement of panels making the comic readable, but otherwise, there seems to be no order at all. I could understand trying to be more original by forgoing the traditional square order of comics, but it seems like all the panels are different sizes and there are simply inexplicable spaces around panels, giving the overall comic a more sloppy appearance.

I can't say that I'm a big fan of the day-night comic background idea either. Granted, it's a fun idea, but there's never any good reason to have the comic background looking as busy as it is, as it detracts visually from the main event - the comic. I'd stick with solid colors.