What is it? What happened to the cursed family in OoT? Why did it happen?

Maybe it says why in the game. I don't remember, since it was kinda long since I played it. But I figured it would be fun to see if anyone knew the origin of the spider curse.

This could perhaps be the most obvious thread in the forum. Maybe it is as clear as day in the game. But whatever, at least I'll be a little enlightened. Post your thoughts and theories.